Table 2

Effect of tacrolimus on I/R induced changes in tissue biomarker level

Groups

Reduced Glutathione (μg/mg of protein)

MPO Activity

(U/min/mg of protein)

Total Calcium

(ppm/mg of protein)

Normal

72.64 ± 2.91

11.32 ± 1.56

3.49 ± 1.04

Sham

71.31 ± 2.47

12.64 ± 1.37

3.59 ± 0.83

I/R

39.25 ± 1.67^a

134.01 ± 3.91^a

34.61 ± 1.93^a

Vehicle

40.54 ± 1.92^a

138.43 ± 3.51^a

35.19 ± 1.64^a

Tacrolimus (1)

46.47 ± 2.65^a

126.32 ± 1.47^a

31.69 ± 0.57^a

Tacrolimus (2)

63.35 ± 1.69^b

62.79 ± 2.63^b

14.41 ± 2.61^b

Tacrolimus (3)

68.41 ± 1.83^b

41.84 ± 3.92^b

9.16 ± 1.92^b

Data were expressed as mean ± S.E.M. for each group.

a = P < 0.05 vs sham control group,

b = P < 0.05 vs ischemia control group.

Muthuraman and Sood Journal of Brachial Plexus and Peripheral Nerve Injury 2010 5:13   doi:10.1186/1749-7221-5-13