Figure 1.

Enzyme histochemical reaction product in the fifth lumbar dorsal root ganglion from control and diabetic mice. (A,B) Cytochrome oxidase reaction product in sections from control (A) and the diabetic (B) mice. Diabetic mice display reduced levels of CO reaction product compared to control. Quantitative analysis revealed a decrease in CO reaction product density in small neuronal somata. (C,D) NADPH-diaphorase reaction product in sections from control (C) and diabetic (D) mice. Diabetic mice display an increase in NADPH-diaphorase reaction product density compared to control. Scale bar in microns.